Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans.

@article{Grassi1998BodyWR,
  title={Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans.},
  author={Guido Grassi and Gino Seravalle and Michele Colombo and Giovanni Battista Bolla and Barbara Cattaneo and Francesco Cavagnini and Giuseppe Mancia},
  journal={Circulation},
  year={1998},
  volume={97 20},
  pages={
          2037-42
        }
}
BACKGROUND Previous studies have shown that sympathetic cardiovascular outflow is increased in obese normotensive subjects and that this increase is associated with a baroreflex impairment. The purpose of this study was to determine whether these abnormalities are irreversible or can be favorably affected by body weight reduction. METHODS AND RESULTS In 20 obese normotensive subjects (age, 31.3+/-1.7 years; body mass index, 37.6+/-0.9 kg/m2, mean+/-SEM), we measured beat-to-beat arterial… CONTINUE READING
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