Body measurements, estrogen availability and the risk of human breast cancer: a case-control study.

@article{Bruning1992BodyME,
  title={Body measurements, estrogen availability and the risk of human breast cancer: a case-control study.},
  author={Peter F Bruning and Johannes M. G. M. Bonfrer and Augustinus A. M. Hart and Paul A H van Noord and Henk van der Hoeven and Hubertine J. A. Collette and J. J. Battermann and M. de Jong-Bakker and Willem J. Nooijen and F. de Waard},
  journal={International journal of cancer},
  year={1992},
  volume={51 1},
  pages={14-9}
}
Recent studies on lifestyle-related mechanisms involved in cardiovascular risk offer important clues for a better understanding of breast-cancer epidemiology. Central body-fat distribution promoted by an affluent dietary intake and a sedentary lifestyle over many years is related to elevated serum triglycerides and free fatty acids, with lower levels of sex-hormone-binding globulin (SHBG). The resulting greater availability of estradiol not bound to SHBG could help to explain the high breast… CONTINUE READING

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