Body iron and individual iron prophylaxis in pregnancy—should the iron dose be adjusted according to serum ferritin?

@article{Milman2006BodyIA,
  title={Body iron and individual iron prophylaxis in pregnancy—should the iron dose be adjusted according to serum ferritin?},
  author={Nils Thorm Milman and Keld-Erik Byg and Thomas Bergholt and Lisbeth Eriksen and Anne-Mette Hvas},
  journal={Annals of Hematology},
  year={2006},
  volume={85},
  pages={567-573}
}
This study aims to evaluate iron prophylaxis in pregnant women from the individual aspect, i.e. according to serum ferritin levels at the beginning of pregnancy, and to assess which dose of iron would be adequate to prevent iron deficiency (ID) and iron deficiency anaemia (IDA) during pregnancy and postpartum. A randomised, double-blind study comprising 301 healthy Danish pregnant women allocated into four groups taking ferrous iron (as fumarate) in doses of 20 mg (n=74), 40 mg (n=76), 60 mg (n… 
Iron prophylaxis in pregnancy—general or individual and in which dose?
TLDR
In the Western countries there is no consensus on iron prophylaxis to pregnant women, but suggested guidelines are ferritin >70 μg/l: no iron supplements, and individual iron proPHylaxis according to serumferritin concentration should be preferred to general prophYLaxis.
The Effectiveness of Different Doses of Iron Supplementation and the Prenatal Determinants of Maternal Iron Status in Pregnant Spanish Women: ECLIPSES Study
TLDR
Iron supplementation should be adjusted to early pregnancy levels of Hb and iron stores, and Mutations of the HFE gene should be evaluated in women with high Hb levels in early pregnancy.
Serum ferritin, soluble transferrin receptor, and total body iron for the detection of iron deficiency in early pregnancy: a multiethnic population-based study with low use of iron supplements.
TLDR
The prevalence of iron deficiency was significantly higher by all measures in South Asian, Sub-Saharan African, and Middle Eastern than in Western European women, and the ethnic differences persisted after adjusting for confounders.
Effect of different doses of iron supplementation during pregnancy on maternal and infant health
TLDR
The higher the doses of iron supplementation, the lower the percentages of iron depletion at partum, iron deficiency anaemia, and preterm deliveries as well as a higher birth weight of the newborn.
Prevalence of iron deficiency states and risk of haemoconcentration during pregnancy according to initial iron stores and iron supplementation
TLDR
The prevalence of ID and IDA was high in late pregnancy in healthy pregnant women, particularly in those with initial ID and/or those not taking supplements, and the risk of haemoconcentration was high at delivery, but did not seem to be promoted by Fe supplementation.
Iron status, and factors affecting iron status during the third trimester of pregnancy in Sudanese
TLDR
Gravidity, gestational age, close birth spacing, and lack of iron supplementation are risk factors for iron deficiency during pregnancy.
Prepartum anaemia: prevention and treatment
TLDR
Profound IDA has serious consequences for both woman and foetus and requires prompt intervention with intravenous iron, and is efficiently prevented by oral iron supplements in doses of 30–40 mg ferrous iron taken between meals from early pregnancy to delivery.
Intravenous iron isomaltoside versus oral iron supplementation for treatment of iron deficiency in pregnancy: protocol for a randomised, comparative, open-label trial
TLDR
This randomised comparative, open-label, single-centre, phase IV trial is designed to prevent iron deficiency anaemia defined by a low level of haemoglobin throughout the trial, which can be used to consider the optimal 2nd line of treatment in iron-deficient pregnant women.
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TLDR
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TLDR
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TLDR
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