Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses.

@article{Amato1993BodyCB,
  title={Body composition, bone metabolism, and heart structure and function in growth hormone (GH)-deficient adults before and after GH replacement therapy at low doses.},
  author={Giovanni Amato and Carlo Carella and Serafino Fazio and Giovanni La Montagna and Antonio Cittadini and David Baltimore Walter Neupert G{\"u}nter Blobel George Pala Sabatini and C Marciano-Mone and Luigi Sacc{\'a} and Antonio Bellastella},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1993},
  volume={77 6},
  pages={1671-6}
}
The effects of recombinant GH doses (10 micrograms/kg.day, 3 times a week for 6 months) lower than those previously used in the treatment of GH-deficient adults (GHDA) on body composition, bone mineral content, and heart structure and function were investigated in seven (six males and one female, aged 25-27 yr) GHDA. They were studied before treatment, after treatment, and 6 months after stopping therapy, and findings were compared with those for 20 sex-, age-, and body mass index-matched… CONTINUE READING