Bocavirus infection induces mitochondrion-mediated apoptosis and cell cycle arrest at G2/M phase.

@article{Chen2010BocavirusII,
  title={Bocavirus infection induces mitochondrion-mediated apoptosis and cell cycle arrest at G2/M phase.},
  author={Aaron Yun Chen and Yong Luo and Fang Cheng and Yuning Sun and Jianming Qiu},
  journal={Journal of virology},
  year={2010},
  volume={84 11},
  pages={5615-26}
}
Bocavirus is a newly classified genus of the family Parvovirinae. Infection with Bocavirus minute virus of canines (MVC) produces a strong cytopathic effect in permissive Walter Reed/3873D (WRD) canine cells. We have systematically characterized the MVC infection-produced cytopathic effect in WRD cells, namely, the cell death and cell cycle arrest, and carefully examined how MVC infection induces the cytopathic effect. We found that MVC infection induces an apoptotic cell death characterized by… CONTINUE READING

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signaling pathways Molecular characterization of human parvovirus B 19 genotypes 2 and 3

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Virology • 2010

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