BoLA class I allele diversity and polymorphism in a herd of cattle

  title={BoLA class I allele diversity and polymorphism in a herd of cattle},
  author={Shawn L Babiuk and Benjamin Horseman and Chenhong Zhang and Mik Bickis and Anthony J. Kusalik and Lawrence B. Schook and Mitchell S. Abrahamsen and Reno A Pontarollo},
Major histocompatibility complex class I genes are among the most polymorphic genes characterized. The high level of polymorphism is essential for generating host immune responses. In humans, three distinct genomic loci encode human leukocyte antigen (HLA) class I genes, allowing individuals to express up to six different HLA class I molecules. In cattle, the number of distinct genomic loci are currently at least six, and the number of different bovine leukocyte antigens (BoLA) class I… CONTINUE READING


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Nomenclature for factors of the BoLA system, 1996: report of the ISAG BoLA Nomenclature Committee

  • CJ Davies, L Andersson, +6 authors GC Russell
  • Anim Genet
  • 1997
Highly Influential
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