Bni1p regulates microtubule-dependent nuclear migration through the actin cytoskeleton in Saccharomyces cerevisiae.

@article{Fujiwara1999Bni1pRM,
  title={Bni1p regulates microtubule-dependent nuclear migration through the actin cytoskeleton in Saccharomyces cerevisiae.},
  author={Toshimichi Fujiwara and Kazuma Tanaka and Eri Inoue and Mitsuhiro Kikyo and Yoshimi Takai},
  journal={Molecular and cellular biology},
  year={1999},
  volume={19 12},
  pages={8016-27}
}
The RHO1 gene encodes a yeast homolog of the mammalian RhoA protein. Rho1p is localized to the growth sites and is required for bud formation. We have recently shown that Bni1p is one of the potential downstream target molecules of Rho1p. The BNI1 gene is implicated in cytokinesis and the establishment of cell polarity in Saccharomyces cerevisiae but is not essential for cell viability. In this study, we screened for mutations that were synthetically lethal in combination with a bni1 mutation… CONTINUE READING
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