Bluues server: electrostatic properties of wild-type and mutated protein structures

@article{Walsh2012BluuesSE,
  title={Bluues server: electrostatic properties of wild-type and mutated protein structures},
  author={Ian Walsh and Giovanni Minervini and Alessandra Corazza and Gennaro Esposito and Silvio C. E. Tosatto and Federico Fogolari},
  journal={Bioinformatics},
  year={2012},
  volume={28 16},
  pages={2189-90}
}
MOTIVATION Electrostatic calculations are an important tool for deciphering many functional mechanisms in proteins. Generalized Born (GB) models offer a fast and convenient computational approximation over other implicit solvent-based electrostatic models. Here we present a novel GB-based web server, using the program Bluues, to calculate numerous electrostatic features including pKa-values and surface potentials. The output is organized allowing both experts and beginners to rapidly sift the… CONTINUE READING