Blunted hypothalamo-pituitary adrenal axis response to predator odor predicts high stress reactivity

@article{Whitaker2015BluntedHA,
  title={Blunted hypothalamo-pituitary adrenal axis response to predator odor predicts high stress reactivity},
  author={Annie M. Whitaker and Nicholas W Gilpin},
  journal={Physiology & Behavior},
  year={2015},
  volume={147},
  pages={16-22}
}
Individuals with trauma- and stress-related disorders exhibit increases in avoidance of trauma-related stimuli, heightened anxiety and altered neuroendocrine stress responses. Our laboratory uses a rodent model of stress that mimics the avoidance symptom cluster associated with stress-related disorders. Animals are classified as 'Avoiders' or 'Non-Avoiders' post-stress based on avoidance of predator-odor paired context. Utilizing this model, we are able to examine subpopulation differences in… CONTINUE READING

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