Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats.

Abstract

Aging mammals lose the ability to maintain energy balance, exhibiting decreased appetite (anorexia) and impaired ability to maintain body weight. To determine the contribution of hypothalamic neuropeptides, two experiments were performed in male Brown Norway rats. To assess the hypothalamic neuropeptide response to food deprivation, young (Y; 4 mo old… (More)

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@article{WoldenHanson2004BluntedHN, title={Blunted hypothalamic neuropeptide gene expression in response to fasting, but preservation of feeding responses to AgRP in aging male Brown Norway rats.}, author={Tami H. Wolden-Hanson and Brett T. Marck and Alvin M. Matsumoto}, journal={American journal of physiology. Regulatory, integrative and comparative physiology}, year={2004}, volume={287 1}, pages={R138-46} }