Blunted Ventral Striatum Development in Adolescence Reflects Emotional Neglect and Predicts Depressive Symptoms

@article{Hanson2015BluntedVS,
  title={Blunted Ventral Striatum Development in Adolescence Reflects Emotional Neglect and Predicts Depressive Symptoms},
  author={Jamie L. Hanson and Ahmad R. Hariri and D. E. Williamson},
  journal={Biological Psychiatry},
  year={2015},
  volume={78},
  pages={598-605}
}
BACKGROUND Emotional neglect is associated with multiple negative outcomes, particularly increased risk for depression. Motivated by increasing evidence of reward-related ventral striatum (VS) dysfunction in depression, we investigated the role of developmental changes in VS activity on the emergence of depressive symptomatology as a function of emotional neglect. METHODS We examined relationships between longitudinal neuroimaging of reward-related VS activity, assessments of mood, and… CONTINUE READING
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