Blumeaenes A-J, sesquiterpenoid esters from Blumea balsamifera with NO inhibitory activity.

@article{Chen2010BlumeaenesAS,
  title={Blumeaenes A-J, sesquiterpenoid esters from Blumea balsamifera with NO inhibitory activity.},
  author={Ming Chen and Jiang-jiang Qin and Jian-jun Fu and Xiao-jia Hu and Xiao-hua Liu and Wei-dong Zhang and Huizi Jin},
  journal={Planta medica},
  year={2010},
  volume={76 9},
  pages={
          897-902
        }
}
Chemical examination of the ethanol extract of the aerial parts of Blumea balsamifera led to the isolation of ten new sesquiterpenoid esters, blumeaenes A-J (1- 10), with 13 known flavonoids. Their structures were determined mainly by use of 1D and 2D NMR spectroscopic techniques. All sesquiterpenoid esters were tested for their inhibitory activity against LPS-induced NO production in RAW264.7 macrophages. Compounds 1, 4 and 5 showed slight inhibitory effect on the production of NO with IC(50… CONTINUE READING
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