BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells

  title={BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells},
  author={Chi Ming Lee and Yen‐Hao Su and Thanh-Tuan Huynh and Wei-Hwa Lee and Jeng-Fong Chiou and Yen-Kuang Lin and Michael Hsiao and Chih Hsiung Wu and Yuh-Feng Lin and Alexander T. H. Wu and Chi-Tai Yeh},
  journal={Evidence-based Complementary and Alternative Medicine : eCAM},
  • C. Lee, Yen‐Hao Su, C. Yeh
  • Published 26 June 2013
  • Biology
  • Evidence-based Complementary and Alternative Medicine : eCAM
For many malignancies, radiation therapy remains the second option only to surgery in terms of its curative potential. However, radiation-induced tumor cell death is limited by a number of factors, including the adverse response of the tumor microenvironment to the treatment and either intrinsic or acquired mechanisms of evasive resistance, and the existence of cancer stem cells (CSCs). In this study, we demonstrated that using different doses of irradiation led to the enrichment of CD133… 

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