Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.

@article{Dai2013BlueLR,
  title={Blue light rescues mice from potentially fatal Pseudomonas aeruginosa burn infection: efficacy, safety, and mechanism of action.},
  author={Tianhong Dai and Asheesh Gupta and Ying-ying Huang and R Yin and Clinton K. Murray and Mark Steven Vrahas and Margaret E. Sherwood and George P. Tegos and Michael R Hamblin},
  journal={Antimicrobial agents and chemotherapy},
  year={2013},
  volume={57 3},
  pages={1238-45}
}
Blue light has attracted increasing attention due to its intrinsic antimicrobial effect without the addition of exogenous photosensitizers. However, the use of blue light for wound infections has not been established yet. In this study, we demonstrated the efficacy of blue light at 415 nm for the treatment of acute, potentially lethal Pseudomonas aeruginosa burn infections in mice. Our in vitro studies demonstrated that the inactivation rate of P. aeruginosa cells by blue light was… CONTINUE READING

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