Blue light regulated two-component systems: enzymatic and functional analyses of light-oxygen-voltage (LOV)-histidine kinases and downstream response regulators.

@article{Corra2013BlueLR,
  title={Blue light regulated two-component systems: enzymatic and functional analyses of light-oxygen-voltage (LOV)-histidine kinases and downstream response regulators.},
  author={Fernando Corr{\^e}a and Wen-huang Ko and V. Ocasio and Roberto A. Bogomolni and Kevin H Gardner},
  journal={Biochemistry},
  year={2013},
  volume={52 27},
  pages={4656-66}
}
Light is an essential environmental cue for diverse organisms. Many prokaryotic blue light photoreceptors use light, oxygen, voltage (LOV) sensory domains to control the activities of diverse output domains, including histidine kinases (HK). Upon activation, these proteins autophosphorylate a histidine residue before subsequently transferring the phosphate to an aspartate residue in the receiver domain of a cognate response regulator (RR). Such phosphorylation activates the output domain of the… CONTINUE READING

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