Blood volume expansion with hyperoncotic colloids deteriorates allograft function in a canine model of renal transplantation.

@article{Salomon2007BloodVE,
  title={Blood volume expansion with hyperoncotic colloids deteriorates allograft function in a canine model of renal transplantation.},
  author={Caryl Salomon and Daniel Casanova and Gumersindo Solares and C. Qualls and Julio Gonz{\'a}lez-Cotorruelo and Manuel Arias},
  journal={Transplantation proceedings},
  year={2007},
  volume={39 7},
  pages={2112-4}
}
PURPOSE We investigated the effects of acute maximal hydratation with hemoce (H) and dextran-40 (D40) on the postoperative graft function, following renal transplantation (RT) in a canine model. METHODS After induction of anesthesia with pentobarbital (5 mg/kg), 18 beagle dogs were randomized to receive either saline solution to increase the central venous pressure (CVP) to 5 mm Hg (GI); H solution to increase the CVP to 10 mm Hg (GII); or D40 to achieve 15 mm Hg (GIII), before reperfusion. A… CONTINUE READING