Blood-spinal cord barrier response to transection

  title={Blood-spinal cord barrier response to transection},
  author={Linda J. Noble and David S. Maxwell},
  journal={Experimental Neurology},
The integrity of the blood-spinal cord barrier (BSB) distal to a surgical transection was evaluated at the light and electron microscopic levels, using the tracers Evans blue albumin (EBA) and horseradish peroxidase (HRP). At the light microscopic level, the orange fluorescence of the EBA was detected as far as 0.45 mm distal to the transection. The tracer was not only diffusely distributed in the neuropil but also was apparently taken up by ventral horn neurons and glial cells. A feathery halo… CONTINUE READING


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