Blood pressure response to tyramine-enriched meal before and during MAO-inhibition in man: influence of dosage regimen.

@article{Mueller1988BloodPR,
  title={Blood pressure response to tyramine-enriched meal before and during MAO-inhibition in man: influence of dosage regimen.},
  author={Thomas Mueller and R. Gieschke and Walter H. Ziegler},
  journal={Journal of neural transmission. Supplementum},
  year={1988},
  volume={26},
  pages={105-14}
}
In an open study oral tyramine in variable doses was administered to six healthy volunteers under three different conditions: 1) without moclobemide, 2) under moclobemide steady-state conditions (3 X 200 mg moclobemide daily) one hour after moclobemide intake and 3) under moclobemide steady-state conditions simultaneously with moclobemide. It was shown that the amount of tyramine effecting 30-50 mmHg systolic blood pressure increase was roughly doubled when moclobemide was administered together… CONTINUE READING