Blood pressure over-shoot due to acute clonidine (Catapres) withdrawal: studies on arterial and urinary catecholamines and suggestions for management of the crisis.
@article{Hansson1973BloodPO, title={Blood pressure over-shoot due to acute clonidine (Catapres) withdrawal: studies on arterial and urinary catecholamines and suggestions for management of the crisis.}, author={L. Hansson and S. Hunyor}, journal={Clinical science and molecular medicine. Supplement}, year={1973}, volume={45 Suppl 1}, pages={ 181s-3 } }
SUMMARY 1. Clonidine was withdrawn acutely in five hypertensive patients with a documented blood pressure over-shoot after previous temporary cessation of treatment. 2. In all patients a severe rise of systolic and diastolic blood pressure was seen (average 67/58 mmHg). This was accompanied by a number of ‘withdrawal symptoms’, e.g. restlessness, tremor, headaches and nausea. 3. Catecholamines in urine rose from 32 pg/l to 112 pg/l (0.01 <P<0.02) and in arterial blood from 0-52 pg/l to 1 .O pg… CONTINUE READING
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