Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension.

@article{Chen2009BloodPL,
  title={Blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertension.},
  author={J. Chen and B. Heran and J. Wright},
  journal={The Cochrane database of systematic reviews},
  year={2009},
  volume={4},
  pages={
          CD007187
        }
}
BACKGROUND Diuretics are widely prescribed for hypertension not only as a first-line drug but also as a second-line drug. Therefore, it is essential to determine the effects of diuretics on blood pressure (BP), heart rate and withdrawals due to adverse effects (WDAEs) when given as a second-line drug. OBJECTIVES To quantify the additional reduction in systolic blood pressure (SBP) and diastolic blood pressure (DBP) of diuretic therapy as a second-line drug in patients with primary… Expand
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