Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models.

@article{Deforrest1990BloodPL,
  title={Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models.},
  author={J M Deforrest and Thomas L Waldron and Cathy Harvey and B Scalese and S L Mitch and J. Robert Powell and W Petrillo and David W. Cushman},
  journal={Journal of cardiovascular pharmacology},
  year={1990},
  volume={16 1},
  pages={139-46}
}
The blood pressure lowering and renal hemodynamic effects of fosinopril, the chemically novel inhibitor of angiotensin I converting enzyme (ACE), was assessed in conscious animal models. In conscious dogs, intravenous infusion of SQ 27,519 [0.5 mg/kg (1.1 mumol/kg) bolus plus 0.1 mg/kg/min (0.22 mumol/kg/min)], the active moiety of the prodrug fosinopril… CONTINUE READING