Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias.

@article{MacMahon1990BloodPS,
  title={Blood pressure, stroke, and coronary heart disease. Part 1, Prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias.},
  author={Stephen MacMahon and Richard Peto and Jeff Cutler and Rory Collins and Paul D. Sorlie and James Neaton and R C Abbott and Jon Godwin and Alan Dyer and Jeremiah Stamler},
  journal={Lancet},
  year={1990},
  volume={335 8692},
  pages={765-74}
}
The associations of diastolic blood pressure (DBP) with stroke and with coronary heart disease (CHD) were investigated in nine major prospective observational studies: total 420,000 individuals, 843 strokes, and 4856 CHD events, 6-25 (mean 10) years of follow-up. The combined results demonstrate positive, continuous, and apparently independent associations, with no significant heterogeneity of effect among different studies. Within the range of DBP studied (about 70-110 mm Hg), there was no… CONTINUE READING
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