Blood pressure, stroke, and coronary heart disease Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context

@article{Collins1990BloodPS,
  title={Blood pressure, stroke, and coronary heart disease Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context},
  author={Rory Collins and Richard Peto and Stephen MacMahon and Jon Godwin and Nawab Qizilbash and Patricia R. Hebert and Kim Eberlein and J. O. Taylor and Charles H. Hennekens and Nicholas H. Fiebach},
  journal={The Lancet},
  year={1990},
  volume={335},
  pages={827-838}
}

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Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

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Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context of expectations from prospective epidemiological studies

TLDR
The results indicate the importance of lowering blood pressure in everyone over certain age, rather than measuring it in everyone and treating it in some, and indicate that the benefit is explained by blood pressure reduction itself.
...

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Antihypertensive treatment based on a beta-blocker or on a thiazide diuretic could not be shown to affect the prevention of hypertensive complications, including CHD, to a different extent.

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TLDR
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TLDR
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