Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context.

Abstract

There are 14 unconfounded randomised trials of antihypertensive drugs (chiefly diuretics or beta-blockers): total 37,000 individuals, mean treatment duration 5 years, mean diastolic blood pressure (DBP) difference 5-6 mm Hg. In prospective observational studies, a long-term difference of 5-6 mm Hg in usual DBP is associated with about 35-40% less stroke and… (More)

Topics

Cite this paper

@article{Collins1990BloodPS, title={Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context.}, author={R. Collins and R{\'e}ka Pető and S Macmahon and P. H{\'e}bert and Nicholas H. Fiebach and Klaus Eberlein and Johnnie Godwin and Nawab Qizilbash and Jana Taylor and Charles H. Hennekens}, journal={Lancet}, year={1990}, volume={335 8693}, pages={827-38} }