Blood oxidative stress in amyotrophic lateral sclerosis.

  title={Blood oxidative stress in amyotrophic lateral sclerosis.},
  author={Dominique Bonnefont-Rousselot and Lucette Lacomblez and M Jaudon and Sylvie Lepage and François Salachas and Gilbert Bensimon and Catherine Bizard and Val{\'e}rie Doppler and Jacques Delattre and Vincent Meininger},
  journal={Journal of the neurological sciences},
  volume={178 1},
It has been suggested that amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder resulting in motor neuron death, is associated with oxidative damage induced by free radicals. Our study aimed to get an assessment of the blood oxidative stress status in a population of 167 ALS patients (aged 59+/-13 years), treated or not with riluzole, compared with 62 age-matched healthy control subjects (aged 60+/-11 years) simultaneously included in the study. We determined the level of plasma… CONTINUE READING


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