Blood lead concentrations in hereditary hemochromatosis.

  title={Blood lead concentrations in hereditary hemochromatosis.},
  author={James C Barton and Michael A. Patton and Corwin Q. Edwards and Len Griffen and James P. Kushner and Robert Meeks and Rich Leggett},
  journal={The Journal of laboratory and clinical medicine},
  volume={124 2},
We postulated that patients with hereditary hemochromatosis (HH) absorb increased quantities of lead, as do iron-deficient subjects. To test this hypothesis, whole blood lead concentration ([blood Pb]) was quantified by atomic absorption spectrometry in HH homozygotes (n = 44), obligate heterozygotes (n = 19), normal control subjects (n = 33), and abnormal controls, with transfusion-induced iron overload (n = 8). HH homozygotes had higher [blood Pb] than did normal control subjects (5.6 +/- 0.6… CONTINUE READING