Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study

@article{Bernal2002BloodLA,
  title={Blood lactate as an early predictor of outcome in paracetamol-induced acute liver failure: a cohort study},
  author={W. Bernal and N. Donaldson and D. Wyncoll and J. Wendon},
  journal={The Lancet},
  year={2002},
  volume={359},
  pages={558-563}
}
BACKGROUND Although the King's College Hospital (KCH) selection criteria for emergency liver transplantation in paracetamol-induced acute liver failure are widely used, strategies to improve sensitivity and facilitate earlier transplantation are required. We investigated the use of arterial blood lactate measurement for the identification of transplantation candidates. METHODS In a single-centre study, we measured arterial blood lactate early (median 4 h) and after fluid resuscitation (median… Expand
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