Blood group substances, T6 antigen and heterochromatin pattern as species markers in the nude mouse/human skin model.

@article{Graem1984BloodGS,
  title={Blood group substances, T6 antigen and heterochromatin pattern as species markers in the nude mouse/human skin model.},
  author={Niels Graem and Erik Dabelsteen and Niels Tommerup},
  journal={Experimental cell biology},
  year={1984},
  volume={52 4},
  pages={251-9}
}
Antibodies to blood group antigens and to human T6 antigen and the DNA-specific fluorochrome D287/170 were applied to human skin transplanted to nude mice and to the surrounding murine skin. It was found that the two epithelia maintained their characteristic, different blood group B antigen distributions and heterochromatin patterns. Furthermore, it was shown that human Langerhans' cells persisted in the grafted epidermis. During an observation period of until 48 weeks after transplantation… CONTINUE READING