Blood glucose control and the evolution of diabetic retinopathy and albuminuria. A preliminary multicenter trial.

@article{Kroccollaborativestudygroup1984BloodGC,
  title={Blood glucose control and the evolution of diabetic retinopathy and albuminuria. A preliminary multicenter trial.},
  author={Kroccollaborativestudygroup},
  journal={The New England journal of medicine},
  year={1984},
  volume={311 6},
  pages={
          365-72
        }
}
We conducted a prospective multicenter randomized trial to determine both the feasibility of maintaining blood glucose control at differing levels and the effect of improved control on diabetic microangiopathy and albuminuria. Seventy patients with diabetes (low C-peptide level) with nonproliferative retinopathy were randomly assigned to continuous subcutaneous insulin infusion or unchanged conventional injection treatment. At entry, both groups had similar demographic, clinical, and glycemic… CONTINUE READING

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