Blood coagulation system in patients with chronic kidney disease: a prospective observational study

  title={Blood coagulation system in patients with chronic kidney disease: a prospective observational study},
  author={Meng-jie Huang and Ri-bao Wei and Yang Wang and Ting-yu Su and Ping Di and Qing-ping Li and Xi Yang and Ping Li and Xiang-Mei Chen},
  journal={BMJ Open},
Objectives Thromboembolic events are the major factor affecting the prognosis of patients with chronic kidney disease (CKD). Haemostatic alterations are possible causes of these complications, but their roles remain poorly characterised. In the prospective observational study, we investigated the entire coagulation process in patients with CKD to elucidate the mechanisms of their high thromboembolic risk. Methods A total of 95 patients with CKD and 20 healthy controls who met the inclusion… 
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