Blood clonal B cell excess at diagnosis in multiple myeloma: relation to prognosis.

@article{Osterborg1987BloodCB,
  title={Blood clonal B cell excess at diagnosis in multiple myeloma: relation to prognosis.},
  author={Anders Osterborg and Bo N Nilsson and Magnus Bj{\"o}rkholm and G{\"o}ran Holm and Bo M. Johansson and C S Lindemalm and Danny Petterson and A Ahre and H{\aa}kan Mellstedt},
  journal={European journal of haematology},
  year={1987},
  volume={38 2},
  pages={173-8}
}
112 patients with multiple myeloma have been studied at diagnosis for the presence of blood clonal B-cell excess (CBE), defined as a ratio between kappa+ and lambda+ lymphocytes outside the normal range (0.9-3.5). 48 patients (43%) had CBE. The increase in light chain-bearing lymphocytes was always that of the M component light chain isotype. The… CONTINUE READING