Blood-brain exchange routes and distribution of65Zn in rat brain

  title={Blood-brain exchange routes and distribution of65Zn in rat brain},
  author={Peggy A. Franklin and R. G. L. Pullen and Grahame H. Hall},
  journal={Neurochemical Research},
Zinc is essential for normal development and function of the CNS although much is to be learned about brain Zn homeostasis. In these experiments adult male Wistar rats within the weight range 500–600 g were used. Ventriculo-cisternal perfusion was performed to allow the measurement of65Zn fluxes between blood and csf across the choroid plexuses. Blood-brain or blood-cerebrospinal fluid barrier permeability to65Zn has been determined by graphical analysis in experiments that lasted between 5 and… CONTINUE READING


Publications referenced by this paper.
Showing 1-10 of 19 references

Hisfidine-stimulated 6SZn transport at the BBB of the anaesthetised rat

S. Buxani, J. Adu
J. Physiol. 438:121P • 1991
View 2 Excerpts

65Zn transport into brain and other soft tissues of the rat

J. Adu, M.W.B. Bradbury, S. Buxani
J. Physiol. 423:40P • 1990

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1990
View 1 Excerpt

The inhibition of single N - methyl - D - aspartate - activated channels by zinc ions on cultured rat neurons

G. L. Westbrook
J . Physiol . • 1990

The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat

P. Legrendre, G. L. Westbrook
neurons. J. Physiol • 1990
View 2 Excerpts

The movement of 65Zn between blood and brain in the anaesthetised rat

P. A. Franklin, R.G.L. Pullen
J. Physiol. 423:43P • 1990

Similar Papers

Loading similar papers…