Blood-brain barrier transport kinetics of the neuromedin peptides NMU, NMN, NMB and NT.

Abstract

The neuromedin peptides are peripherally and centrally produced, but until now, it is generally believed that they only function as locally acting compounds without any quantitative knowledge about their blood-brain barrier (BBB) passage. Here, we characterize the transport kinetics of four neuromedins (NMU, NMN, NMB and NT) across the BBB, as well as their… (More)
DOI: 10.1016/j.neuropharm.2016.03.051

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