Blood-brain barrier drug targeting: the future of brain drug development.

@article{Pardridge2003BloodbrainBD,
  title={Blood-brain barrier drug targeting: the future of brain drug development.},
  author={William M Pardridge},
  journal={Molecular interventions},
  year={2003},
  volume={3 2},
  pages={90-105, 51}
}
As human longevity increases, the likelihood of the onset of diseases of the brain (and other organs) also increases. Clinical therapeutics offer useful long-term treatments, if not cures, if drugs can be delivered appropriately and effectively. Unfortunately, research in drug transport to the brain has not advanced very far. Through better characterization of the transport systems utilized within the blood-brain barrier, a greater understanding of how to exploit these systems will lead to… CONTINUE READING
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