Blood-brain barrier disruption in multiple sclerosis

@article{Minagar2003BloodbrainBD,
  title={Blood-brain barrier disruption in multiple sclerosis},
  author={Alireza Minagar and Jonathan Steven Alexander},
  journal={Multiple Sclerosis},
  year={2003},
  volume={9},
  pages={540 - 549}
}
The blood-brain barrier (BBB) is a complex organization of cerebral endothelial cells (C EC), pericytes and their basal lamina, which are surrounded and supported by astrocytes and perivascular macrophages. C ollectively these cells separate and form the compartments of the cerebral vascular space and the cerebral interstitium under normal conditions. Without the BBB, the ‘interior milieu’ of the central nervous system (CNS) would be flooded by humoral neurotransmitters and formed blood… 
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TLDR
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