Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses

@inproceedings{Hori2016BloodbasedGE,
  title={Blood-based gene expression signatures of medication-free outpatients with major depressive disorder: integrative genome-wide and candidate gene analyses},
  author={Hiroaki Hori and Daimei Sasayama and Toshiya Teraishi and Noriko Yamamoto and Seiji Nakamura and Miho Ota and Kotaro Hattori and Yoshiharu Kim and Teruhiko Higuchi and Hiroshi Kunugi},
  booktitle={Scientific reports},
  year={2016}
}
Several microarray-based studies have investigated gene expression profiles in major depressive disorder (MDD), yet with highly variable findings. We examined blood-based genome-wide expression signatures of MDD, focusing on molecular pathways and networks underlying differentially expressed genes (DEGs) and behaviours of hypothesis-driven, evidence-based candidate genes for depression. Agilent human whole-genome arrays were used to measure gene expression in 14 medication-free outpatients with… CONTINUE READING