Blood bank issues associated with red cell exchanges in sickle cell disease.

@article{Sarode2006BloodBI,
  title={Blood bank issues associated with red cell exchanges in sickle cell disease.},
  author={Ravindra Sarode and Fevzi Altuntaş},
  journal={Journal of clinical apheresis},
  year={2006},
  volume={21 4},
  pages={
          271-3
        }
}
Sickle cell disease (SCD) patients are prone to develop complications that include stroke, acute chest syndrome, and other crises. Some of these complications require chronic transfusion therapy or red cell exchange (RCE), either for therapeutic or prophylactic reasons. Due to a discrepancy of red cell antigens between African Americans and Caucasians (majority blood donors), the incidence of alloantibody formation is very high, which makes it difficult to find compatible red cell units… CONTINUE READING

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