Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice.

@article{McKay2011BloodAA,
  title={Blood as a surrogate marker for tissue-specific DNA methylation and changes due to folate depletion in post-partum female mice.},
  author={Jill A. McKay and Long Chang Xie and Sarah E Harris and Yi K. Wong and Dianne Ford and John C. Mathers},
  journal={Molecular nutrition & food research},
  year={2011},
  volume={55 7},
  pages={1026-35}
}
SCOPE DNA methylation patterns are tissue specific and may influence tissue-specific gene regulation. Human studies investigating DNA methylation in relation to environmental factors primarily use blood-derived DNA as a surrogate for DNA from target tissues. It is therefore important to know if DNA methylation changes in blood in response to environmental… CONTINUE READING