Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder

@inproceedings{Budd2018BloodMD,
  title={Blood Mitochondrial DNA Content in HIV-Exposed Uninfected Children with Autism Spectrum Disorder},
  author={Matthew A Budd and Kristina Calli and Lindy Samson and Jennifer R. Bowes and Anthony Y Y Hsieh and John C. Forbes and Ari S Bitnun and Joel Singer and Fatima W Kakkar and Ariane Alimenti and Evelyn J Maan and M E Suzanne Lewis and Carole Gentile and H{\'e}l{\`e}ne Cf C{\^o}t{\'e} and Jason C Brophy},
  booktitle={Viruses},
  year={2018}
}
Long-term outcomes of perinatal exposure to maternal antiretroviral therapy in HIV-exposed uninfected (HEU) children are unknown. However, both HIV antiretroviral therapy and autism spectrum disorder (ASD) have been associated with mitochondrial alterations. Leukocyte mitochondrial DNA (mtDNA) content can serve as a marker for mitochondrial dysfunction. In this cross-sectional, nested case-control study, HEU children with ASD were matched approximately 1:3 on age, sex, and ethnicity to HEU… CONTINUE READING
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Pervasive Developmental Disorder in Antiretroviral- and HIV-Exposed, Uninfected Children [Abstract

  • J. Bowes, J. C. Brophy, L. Samson, C. Gentile
  • Can. J. Infect. Dis. Med. Microbiol
  • 2011
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