Blood Epstein-Barr virus DNA load and risk of progression to AIDS-related systemic B lymphoma.

@article{LeruezVille2012BloodEV,
  title={Blood Epstein-Barr virus DNA load and risk of progression to AIDS-related systemic B lymphoma.},
  author={Marianne Leruez-Ville and R{\'e}monie Seng and Patrice Morand and Faroudy Boufassa and François Bou{\'e} and Christiane Deveau and Christine Rouzioux and C{\'e}cile Goujard and J M Seigneurin and Laurence Meyer},
  journal={HIV medicine},
  year={2012},
  volume={13 8},
  pages={479-87}
}
BACKGROUND AIDS-related lymphoma (ARL) remains the main cause of AIDS-related deaths in the combined antiretroviral therapy (cART) era. Although most ARLs are associated with the Epstein-Barr virus (EBV), whether patients with high EBV burden are more at risk of developing ARL is unknown. This study investigated the relationship between high blood EBV DNA loads and subsequent progression to ARL. METHODS We identified 43 cases of ARL diagnosed between 1988 and 2007 within two cohorts (ANRS… CONTINUE READING
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