Blood Eosinophil Beta1-Integrin Activation Correlates with Eosinophilic Esophagitis (EoE) Disease Activity

@article{Johansson2018BloodEB,
  title={Blood Eosinophil Beta1-Integrin Activation Correlates with Eosinophilic Esophagitis (EoE) Disease Activity},
  author={Mats W. Johansson and Michael D Evans and Elizabeth M. McKernan and Paul S. Fichtinger and Evelyn L. Angulo and Deane F Mosher and Shelly Cook and Eric A. Gaumnitz and Sameer K. Mathur},
  journal={The Journal of Allergy and Clinical Immunology},
  year={2018},
  volume={141}
}
Heterogeneity of Intestinal Tissue Eosinophils: Potential Considerations for Next-Generation Eosinophil-Targeting Strategies
TLDR
The growing evidence for functional sub-phenotypes of intestinal tissue eosinophils is reviewed, with emphasis on the multifactorial pressures that shape and diversify eOSinophil identity and potential targets to inform next-generation eos inophil-targeting strategies designed to restrain inflammatory eosInophil functions while sustaining homeostatic roles.