• Corpus ID: 212476800

Blood Brain Barrier Crossing for Therapeutic and Diagnostic Agents

@inproceedings{Shatzmiller2019BloodBB,
  title={Blood Brain Barrier Crossing for Therapeutic and Diagnostic Agents},
  author={Shimon E Shatzmiller and Inbal Lapidot and Galina M. Zats},
  year={2019}
}
New studies are guiding researchers toward creative ways to open this barrier and “trick” it into allowing medicines to enter. Non-polar agents can cross the blood-brain barrier far easier than polar molecules. This selectivity poses a problem if we have a polar agent that could be extremely effective in treating a disorder. However, scientists have come up with some creative solutions. Non-polar agents are lipophilic, which means they cross the blood-brain barrier by diffusing through the… 
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6 Citations

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