Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity

@article{Gerber2013BloodBorneCS,
  title={Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity},
  author={Alan Gerber and Cyril J. D. Esnault and Gr{\'e}gory Aubert and Richard Treisman and François Pierre Pralong and Ueli Schibler},
  journal={Cell},
  year={2013},
  volume={152},
  pages={492-503}
}
In peripheral tissues circadian gene expression can be driven either by local oscillators or by cyclic systemic cues controlled by the master clock in the brain's suprachiasmatic nucleus. In the latter case, systemic signals can activate immediate early transcription factors (IETFs) and thereby control rhythmic transcription. In order to identify IETFs… CONTINUE READING