Blood Biomarkers for Evaluation of Perinatal Encephalopathy

  title={Blood Biomarkers for Evaluation of Perinatal Encephalopathy},
  author={E. Graham and I. Burd and A. Everett and F. Northington},
  journal={Frontiers in Pharmacology},
  • E. Graham, I. Burd, +1 author F. Northington
  • Published 2016
  • Medicine
  • Frontiers in Pharmacology
  • Recent research in identification of brain injury after trauma shows many possible blood biomarkers that may help identify the fetus and neonate with encephalopathy. Traumatic brain injury shares many common features with perinatal hypoxic-ischemic encephalopathy. Trauma has a hypoxic component, and one of the 1st physiologic consequences of moderate-severe traumatic brain injury is apnea. Trauma and hypoxia-ischemia initiate an excitotoxic cascade and free radical injury followed by the… CONTINUE READING
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