Blocking of influenza virus-induced cell-mediated cytotoxicity by hemagglutinin-specific monoclonal antibody.

Abstract

The relative importance of three major proteins of influenza virus in the mechanism of induction of cell-mediated cytotoxicity (natural killer cell activity) was assessed by an overnight chromium-51-release assay using radiolabeled K-562 cells as target cells and Ficoll-Hypaque-purified peripheral-blood lymphocytes as effector cells. Incubation of… (More)

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