Blocking metabotropic glutamate receptor subtype 5 relieves maladaptive chronic stress consequences.

Abstract

Etiology and pharmacotherapy of stress-related psychiatric conditions and somatoform disorders are areas of high unmet medical need. Stressors holding chronic plus psychosocial components thereby bear the highest health risk. Although the metabotropic glutamate receptor subtype 5 (mGlu5) is well studied in the context of acute stress-induced behaviors and… (More)
DOI: 10.1016/j.bbi.2016.08.007

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