Blocking innate immunity to slow the progression of chronic kidney disease


Chronic inflammation is present in almost every biopsy of patients with chronic kidney disease. It is independent of the cause of kidney injury and can be detected in acute kidney failure and chronic kidney allograft nephropathy, autoimmune diseases like lupus nephritis or granulomatosis with polyangiitis, and even diabetic nephropathy. Chronic inflammation… (More)
DOI: 10.1007/s00210-014-1031-z