Blocking effect of tripelennamine on histamine--induced positive chronotropic and inotropic responses of the dog atrium.

  • Sota Chiba
  • Published 1976 in The Tohoku journal of experimental medicine


The effects of histamine on inotropic and chronotropic activity were investigated in isolated canine atrium preparations which were suspended in a bath and perfused with arterial blood from a carotid artery of heparinized support dog. Histamine administered into the cannulated sinus node artery in a dose range of 0.3-100 mug produced dose-related positive… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics