Blocking N-cadherin function disrupts the epithelial structure of differentiating neural tissue in the embryonic chicken brain.

@article{GnzlerOdenthal1998BlockingNF,
  title={Blocking N-cadherin function disrupts the epithelial structure of differentiating neural tissue in the embryonic chicken brain.},
  author={S I G{\"a}nzler-Odenthal and Christoph Redies},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 14},
  pages={5415-25}
}
The cell adhesion molecule N-cadherin is ubiquitously expressed in the early neuroepithelium, with strongest expression in the ependymal lining. We blocked the function of N-cadherin during early chicken brain development by injecting antibodies against N-cadherin into the tectal ventricle of embryos at 4-5 d of incubation [embryonic day 4 (E4)-E5]. N-cadherin blockage results in massive morphological changes in restricted brain regions. At approximately E6, these changes consist of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 41 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 64 references

Embryologische und morphologische Studien über das Zwischenhirn beim Huhn

  • H Rendahl
  • Acta Zool (Stockh)
  • 1924
Highly Influential
5 Excerpts

Similar Papers

Loading similar papers…