Blockers of calcium permeability inhibit neurite extension and formation of neuromuscular synapses in cell culture.

@article{SurezIsla1984BlockersOC,
  title={Blockers of calcium permeability inhibit neurite extension and formation of neuromuscular synapses in cell culture.},
  author={Benjam{\'i}n A Su{\'a}rez-Isla and D J Pelto and Jamie Thompson and Stanley I. Rapoport},
  journal={Brain research},
  year={1984},
  volume={316 2},
  pages={263-70}
}
Growth of neurites from trypsin-dissociated retinal neurons from chick embryos is very sensitive to the extracellular calcium concentration. Blockers of calcium permeability such as Co2+, Mn2+, La3+ and nitrendipine, when added to dissociated neurons, decrease the fraction of cells that extend neurites and the rate of neurite growth without influencing cell-substratum adhesion or survival capacity. Inhibition is concentration dependent, is related to the age of the donor chick embryo and can be… CONTINUE READING

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